Disease: Primary biliary cirrhosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VTCN1 Q7Z7D3 V-set domain containing T cell activation inhibitor 1 Enzyme modulator 1.4E-12 0.529 0.692
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
TRIM21 P19474 tripartite motif containing 21 3.4E-09 0.485 0.808
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFSF4 P23510 TNF superfamily member 4 Signaling 4.9E-02 0.540 0.808
TNFSF13B Q9Y275 TNF superfamily member 13b 0.98 0.460 0.731
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR3 O15455 toll like receptor 3 Receptor 1.6E-07 0.427 0.885
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
SOCS1 O15524 suppressor of cytokine signaling 1 Enzyme modulator 0.59 0.445 0.808
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
SLC22A1 O15245 solute carrier family 22 member 1 Transporter 1.5E-22 0.556 0.731
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
POU2F1 P14859 POU class 2 homeobox 1 0.90 0.558 0.769